Postgraduate Courses
BIEN
Bioengineering
- BIEN 5001Responsible Conduct of Biomedical and Biotechnology Research[3-0-0:3]Co-list withLIFS 5001Exclusion(s)LIFS 5001BackgroundSome knowledge of general biology concepts, equivalent to introductory biology at the undergraduate levelDescriptionThis course will present some of the most common ethical issues encountered in biomedical research and biotechnology. Students will engage in active discussion to provide deeper understanding of each issue. The objective of this course is to raise awareness of the ethical issues around biomedical/bioengineering research, and encourage critical and responsible consideration of research conduct. Topics covered will fall into three categories: 1) Research integrity, 2) Applied ethics in biological research and biotechnology, and 3) Contemporary ethical issues arisen from emerging biotechnologies. Graded P or F.Intended Learning Outcomes
On successful completion of the course, students will be able to:
- 1.Describe potential important ethical issues that biomedical researchers may face in their careers.
- 2.When presented with a case or specific scenario, identify the explicit or potential ethical issues, arguments, and perspectives arising from the case or scenario.
- 3.Critically analyze and evaluate ethical issues revolving around contemporary biomedical/life science research in a contextual manner, and form and justify their own position on these ethical issues.
- 4.Recall and describe key principles, policies, and regulations relevant to the ethical and responsible conduct of research (e.g. Nuremberg Code).
- 5.Identify administrative or other resources on campus that researchers can access to seek assistance with ethical issues they may be facing.
- 6.Communicate and present ideas to others in a clear and critical manner about complex issues, both in presentation and written format.
- 7.Engage in open and thoughtful discussions with peers on complex ethical issues.
- BIEN 5010Molecular Biology for Bioengineering[3-0-0:3]DescriptionThe course introduces the basics of cell biology, molecular biology techniques, and discusses the principles of macromolecular interactions in those contexts. We will also discuss various applications of these techniques and how combined with engineering concepts, they have contributed to innovations and breakthrough tools in the world of basic research and medicine. Topics to cover include: overview of basic molecular biology and macromolecular interactions; basic biophysical structures, imaging and characterization techniques; molecular engineering; biodevices; and genomics. Active student discussion is required and students will also do a final project team presentation on a current bioengineering topic.Intended Learning Outcomes
On successful completion of the course, students will be able to:
- 1.Describe the central dogma of molecular biology, and be able to recall the various molecular components (molecules, proteins/enzymes) involved in the components of the central dogma. Describe their main physical features and select appropriate tools/techniques for characterizing them.
- 2.Explain the mechanisms and functions of basic molecular biology assays, including PCR, qPCR, gel electrophoresis, molecular cloning, protein separation and purification; be able to analyze and interpret results of above assays.
- 3.Compare different types of imaging tools, and describe their usage and importance in modern biotechnology/medicine.
- 4.Explain what a stem cell is, and compare differences between embryonic stem cells, fetal stem cells, adult stem cells, and induced pluripotent cells; recall modern applications of stem cell therapies, and explain the mechanism of action for these therapies; describe current major challenges in using stem cell therapies in the clinic.
- 5.Explain and critique recent breakthroughs in molecular biology and bioengineering fields, including those outside your research area; be able to suggest potential applications of these new technologies to a relevant clinical challenge.
- 6.Present and discuss the taught ideas and concepts with peers with clarity and evidence-based reasoning; collaborate with team mates with positive attitude and strong work ethic in a group project setting.
- BIEN 5040Introduction to Neural Engineering[3-0-0:3]DescriptionThis course will provide a survey of Neuroscience and Neuroengineering research areas to provide our research postgraduate students a broad appreciation of interdisciplinary research in context. The course aims to help student recognize and understand how knowledge from science and engineering interface in this interdisciplinary application. Concepts such as neural interfacing and neural prosthesis will be introduced so that students can understand the impact of the latest technologies. The course will enhance the vision of the students and encourage them to work in future inter-disciplinary research fields.Intended Learning Outcomes
On successful completion of the course, students will be able to:
- 1.Obtain a holistic view of systems neuroscience fundamentals and methods.
- 2.Recognize the neuroanatomy and understand the basic functions.
- 3.Write a literature review on a topic within systems neuroscience.
- 4.Explain basic neural coding theory and computation method.
- 5.Enhance the knowledge in related area, such as neural engineering.
- BIEN 5050Global Health Ethics[2-1-0:3]Previous Course Code(s)BIEN 6930ADescriptionThrough real-time videoconferencing with participants from different countries such as the United States, United Kingdom, Australia, Mexico, and Philippines, this ONLINE course aims at helping students learn the definitions of global health ethics and bioethics, the different protocol and systems in place to ensure adherence to ethical principles, and how different stakeholders and cultures may interpret ethics differently. Through case studies on ethical challenges from real-world situations, students will analyze and discuss the complexities of global health practice and research ethics in a global context. This course is co-offered with the University of Southern California. Besides the joint LIVE sessions, face-to-face sessions and group projects are also arranged for the introduction of background knowledge, case studies, group project discussion, and technical support.Intended Learning Outcomes
On successful completion of the course, students will be able to:
- 1.Articulate the important ethical considerations of biomedical research, basic and clinical, involving human subjects.
- 2.Outline the unique ethical and social implications of conducting such research in developing countries of different economic status.
- 3.Identify key trends and emerging issues in global health ethics.
- 4.Analyze situations of ethical challenges in global health practice and research from diverse perspectives.
- 5.Appreciate the role culture and religion play in the development of a sense of right and wrong and views on ethics and how protocol fitting to the local context can be justified
- 6.Describe best practices in ethical health research and practice to protect human subjects and their legal right
- BIEN 5060Fundamentals and Applications of Sensing Technologies in Healthcare[3-0-0:3]Previous Course Code(s)BIEN 6930CExclusion(s)BEHI 5004BackgroundStudents are expected to have prior knowledge on general chemistry, biology, and thermodynamicsDescriptionThe course will introduce the basic concepts in detection of biosignals. Students will learn about the biosensing components, transduction mechanisms, novel materials in sensing, and analytical techniques to capture diverse health information. The course will also touch upon the physical and chemical sensors used for healthcare applications. We will also discuss about the emerging flexible, wearable technology toward personalized healthcare. Students will have opportunities to design and propose biosensors and bioelectronics at the end of the course.Intended Learning Outcomes
On successful completion of the course, students will be able to:
- 1.Explain how biosensors work.
- 2.Describe different techniques for bio-signal determination.
- 3.Evaluate biosensors performance.
- 4.Propose biosensors for real world applications.
- BIEN 5070Synthetic Biology[3-0-0:3]Previous Course Code(s)BIEN 6930DExclusion(s)BEHI 5006DescriptionSynthetic biology, which echoes the assertion “What I cannot create, I do not understand” made by Richard Feynman, has been hailed as a revolution for modern science and technology. Unfledged as it is, the field, arising from the synergistic combination of chemistry, biology, engineering, data science, and information/control theory, has already shown great promise in addressing energy and health-related global challenges. This course aims to expose students with diverse backgrounds to this highly interdisciplinary field and furnish them with necessary guidance and ideas for taking on synthetic biology projects.Intended Learning Outcomes
On successful completion of the course, students will be able to:
- 1.Describe the basic concepts and engineering principles in synthetic biology.
- 2.Describe the central dogma of molecular biology and control strategies of gene replication, transcription, post-transcriptional modification, and translation.
- 3.Describe the genetic parts, devices, circuits, and systems in synthetic biology.
- 4.Explain the design of genetic circuits, including genetic input, biological computing, and output Modules, and describe what Design–Build–Test–Learn (DBTL) cycle is in synthetic biology.
- 5.Explain the mechanisms of synthetic biology tools, including Gibson assembly, Golden Gate assembly, DNA recombination, DNA synthesis, directed evolution, and genome editing.
- 6.Recognize, evaluate, and criticize the design of genetic circuits in scientific literature of synthetic biology.
- 7.Explain real-world applications of synthetic biology.
- 8.Enhance communication skills.
- BIEN 5820Microfluidics and Biosensors[3-0-0:3]Co-list withELEC 5820Exclusion(s)ELEC 5820DescriptionIntroduction to Microfluidics and Biosensors; Overview of microfabrication materials & techniques; microfluidic principles; miniaturized biosensors; micro total analysis system (µTAS) & lab-on-a-chip (LOC) for clinical and research applications.Intended Learning Outcomes
On successful completion of the course, students will be able to:
- 1.Describe core concepts in the field of Microfluidics & Biosensors.
- 2.Describe trends and motivations in the field of Microfluidics & Biosensors.
- 3.Analyze/critique research articles in the field of Microfluidics & Biosensors.
- 4.Formulate a potential solution for a clinical problem using Microfluidics & Biosensors.
- BIEN 6800Bioengineering Seminar[0-1-0:0]DescriptionSeminar topics presented by students, faculty and guest speakers. Students are expected to attend regularly and demonstrate proficiency in their seminar presentation in accordance with the program requirements. Graded P or F.Intended Learning Outcomes
On successful completion of the course, students will be able to:
- 1.Identify current research of interest in various topics of bioengineering.
- 2.Obtain insights to how peer researchers design and conduct experiments.
- 3.Gain opportunities to make academic and social contacts with the speakers and with research community.
- 4.Demonstrate proficiency in presentation of research outcome coherently and thoroughly (as presenters).
- BIEN 6910-6940Special Topics in Bioengineering[1-4 credit(s)]DescriptionSelected topics in bioengineering of current interest in emerging areas and not covered by existing courses. May be repeated for credit if different topics are covered. May be graded by letter or P/F for different offerings.Intended Learning Outcomes
On successful completion of the course, students will be able to:
- 1.To demonstrate a capability to integrate knowledge and to analyse, evaluate and manage the different aspects of a special topic in bioengineering.
- BIEN 6990MPhil Thesis ResearchDescriptionMaster's thesis research supervised by a faculty member. A successful defense of the thesis leads to the grade Pass. No course credit is assigned.Intended Learning Outcomes
On successful completion of the course, students will be able to:
- 1.To demonstrate a capability to research and development work.
- 2.To demonstrate the capability to create, analyse and critically evaluate different technical solutions.
- 3.To demonstrate the capability to critically and systematically integrate knowledge.
- 4.To demonstrate the capability to clearly present and discuss the conclusions as well as the knowledge and arguments that form the basis for these findings in written and spoken English.
- 5.To demonstrate a consciousness of the ethical aspects of research and development work.
- BIEN 7990Doctoral Thesis ResearchDescriptionOriginal and independent doctoral thesis research. A successful defense of the thesis leads to the grade Pass. No course credit is assigned.Intended Learning Outcomes
On successful completion of the course, students will be able to:
- 1.To demonstrate a capability to research and development work
- 2.To demonstrate the capability to create, analyse and critically evaluate different technical solutions.
- 3.To demonstrate the capability to critically and systematically integrate knowledge.
- 4.To demonstrate the capability to clearly present and discuss the conclusions as well as the knowledge and arguments that form the basis for these findings in written and spoken English.
- 5.To demonstrate a consciousness of the ethical aspects of research and development work.